Autologous Retinal Transplantation Using a Retinotomy Edge Graft for Macular Hole During Complex PVR Retinal Detachment Repair

Posted By: Sean Berkowitz on August 5, 2026

This video demonstrates autologous retinal transplantation (ART) for closure of a full-thickness macular hole during repair of a complex proliferative vitreoretinopathy (PVR) retinal detachment. The graft is harvested directly from the relaxing retinotomy edge, avoiding a separate donor site. Medium-term perfluoro-n-octane tamponade and adjunctive serial intravitreal methotrexate are used to optimize retinal reattachment and reduce recurrent PVR.